Immunology (IMUN)

IMUN 506 Immune Mechanisms

This is an introductory graduate course which surveys most areas of immunology. It is assumed that students have a background in biochemistry and molecular biology, and at least some familiarity with immunological concepts. Topics covered include the major histocompatibility complex, structure of antibodies and T cell receptors, antigen-antibody interactions, the generation of diversity of immunoglobulins and B cells, antigen presentation, and immunological tolerance.

Taught by: Michael May

Course usually offered in fall term

Prerequisite: Permission of instructor

Activity: Lecture

1 Course Unit

Notes: 4 h. 1 c.u. Monday/Wednesday/Friday

IMUN 507 Immunopathology

The relationship between basic immunology and clinical immunologic diseases is emphasized. Course lecturers represent University faculty who are established investigators in immunological research and established clinical immunologists. Course topics include plasma protein systems; B cell, T cell, macrophage immunology; immunohematology; tumor immunology; benign and malignant, immunoproliferative disorders; neuro-immunology; pulmonary immunology; renal immunology; immune complex disease and immunoregulatory abnormalities.

Taught by: Michael May and Erica Stone

Course usually offered in fall term

Prerequisites: IMUN 506 and permission of instructor

Activity: Lecture

1 Course Unit

Notes: 2 h. 1 c.u. Tuesday/Thursday

IMUN 508 Immune Responses

This course is designed to (1) extend the basic immunology principles addressed in 506, and (2) apply the fundamental principles of the mechanism of immune recognition and development presented in 506 to the immune response in health and disease in vivo. The course is designed as a series of minicourses which may change from year to year. Each minicourse will cover an important topic in immunology in detail. Students must take three minicourses over the Spring semester and must take at least one each from the basic and applied immunology categories (see below). The course will be taught as formal lectures on Monday and Wednesday and a diThe minicourses will be taught as a combination of formal lectures and seminar-format discussions of relevant literature. Each minicourse will have a slightly different format. The minicourses will consist of 6 hours/week for 4 weeks. The semester will be divided into 3 sessions with between 2 to 3 minicourses offered each session. Progress in the course will be evaluated by an exam/paper at the end of each minicourse and class participation. The exams will require students to incorporate the knowledge and thinking gained from the in depth analyses of these topics.

Taught by: Peter Felsburg, VMD., Ph.D. and Kate Sullivan, M.D., Ph.D.

Course usually offered in spring term

Prerequisites: IMUN 506 or equivalent and permission of instructor

Activity: Lecture

1 Course Unit

Notes: Taught Monday, Wednesday Friday, 9:00am-11:00am. 6 hours, 2 cu.

IMUN 520 Tutorials in Immunology

This tutorial course is designed to provide students with an in-depth knowledge of a specific branch of Immunology. The tutorial can be used to enable students to become more deeply acquainted with the literature related to their thesis projects or to expand on a topic that the student found interesting in one of their basic courses. The course is currently the only immunology elective and is, therefore, required for all Immunology Graduate Group students. It is also open as an elective to BGS students who meet the prerequisite. The tutorial course will be examined by the program director and the tutorial leader and the grade will be based on a written paper on the subject studied (5 to 10 typewritten pages) and by an oral presentation of the paper (15 to 20 minutes).

Taught by: Randy Cron, M.D., Ph.D.

Course usually offered in fall term

Prerequisites: A senior undergraduate, graduate or professional school course in Immunology.

Activity: Seminar

1 Course Unit

IMUN 599 Immunology Faculty Research Seminar

Mandatory attendance at weekly research presentations by graduate group faculty.

Taught by: Laura Su and Gregory Beatty

One-term course offered either term

Prerequisite: Permission of Graduate Group Chair

Activity: Independent Study

0.5 Course Units

IMUN 605 Current Topics in Cellular and Molecular Immunology

Recent developments in basic cellular and molecular immunology are discussed by students using the current literature as a resource. This course reinforces and expands upon concepts presented in immunology 506. Students gain experience in critically evaluating current literature and orally presenting and defending their ideas. In the first part of the course, students presetn one or two papers relevant to a current topic in immunology. In the second part, the students each select a research topic and write and defned orally a small research proposal. Course aims are to provide more in-depth knowldege in specific and timely areas of immunologic research. In addition, the course encourages the development of oral presentation skills and the ability to critically evaluate published research and the ideas of one's peers.

Taught by: Philip Scott, Ph.D., and Laurence Turka, M.D.

Course usually offered in spring term

Prerequisite: IMUN 506 or permission of instructor

Activity: Lecture

1 Course Unit

IMUN 607 Grant Writing

This course will introduce the student to basic principles of grant writing. In this regard a primary objective of the course is to teach you how to describe your ideas and experimental objectives in a clear and concise manner within the standard NIH grant format. To accomplish this, you will be required to write an NIH, "RO1" type grant proposal based on your current laboratory project.

Taught by: Andrew Wells, Bruce Freedman, Michael Cancro

Course usually offered in spring term

Prerequisite: IMUN 506/507 and/or permission of instructor

Activity: Seminar

1 Course Unit

IMUN 609 Vaccines and Immune Therapeutics

The goal of the Vaccines course is to expand on student s general understanding of the immune system and to focus this understanding towards the application of vaccination. Furthermore the course will give the student a sense of how these principles are applied to vaccine and immune therapeutic development. The course covers basic science as well as the Clinical, Ethical & Political implications of Modern Vaccines. Initial lectures will review immune mechanisms believed to be responsible for vaccine induced protection from disease. Subsequent lectures build on this background to explore the science of vaccines for diverse pathogens, including agents of bioterrorism as well as vaccines for cancer. An appreciation for the application of laboratory science to the clinical development of vaccines is provided in the next section of the course along with lectures that focus on the ethical implications of vaccines in different situations. The financial implications of specific vaccines and their impact on the global community, is a specific focus of the course.

Taught by: David Weiner, Ph.D., and Paul Offit, M.D.

Course usually offered in fall term

Also Offered As: CAMB 609

Prerequisites: The course is intended for graduate students or Medical Students in various MS, Ph.D. or MD/Ph.D. programs on the campus as well as local scientists and professionals in the community. As a prerequisite students should have taken biology, biochemistry or immunology courses at the advanced college level.

Activity: Lecture

1 Course Unit

IMUN 699 Laboratory Rotation

Laboratory research conducted under a faculty advisor. Three different rotations covering usually the fall semester of the first year through the fall semester of the second year are required of all Immunology Ph.D. students. Students will defend the rotation research in their Preliminary Exams

Taught by: Immunology Graduate Group Faculty

One-term course offered either term

Prerequisites: Permission of instructor and immunology chair.

Activity: Laboratory

1 Course Unit

IMUN 799 Independent Study

Activity: Independent Study

1 Course Unit

IMUN 899 Predissertation Lab

Activity: Laboratory

1 Course Unit